Akshay S Desai Selected Research

Enalapril

1/2022	Effect of sacubitril/valsartan on investigator-reported ventricular arrhythmias in PARADIGM-HF.
1/2021	Hemodynamic Effects of Sacubitril-Valsartan Versus Enalapril in Patients With Heart Failure in the EVALUATE-HF Study: Effect Modification by Left Ventricular Ejection Fraction and Sex.
1/2021	Effect of sacubitril/valsartan vs. enalapril on changes in heart failure therapies over time: the PARADIGM-HF trial.
1/2021	Clinical Characteristics and Outcomes of Patients With Heart Failure With Reduced Ejection Fraction and Chronic Obstructive Pulmonary Disease: Insights From PARADIGM-HF.
9/2019	Effect of Sacubitril-Valsartan vs Enalapril on Aortic Stiffness in Patients With Heart Failure and Reduced Ejection Fraction: A Randomized Clinical Trial.
1/2019	Reduced loop diuretic use in patients taking sacubitril/valsartan compared with enalapril: the PARADIGM-HF trial.
1/2019	Clinical Outcomes in Patients With Acute Decompensated Heart Failure Randomly Assigned to Sacubitril/Valsartan or Enalapril in the PIONEER-HF Trial.
4/2018	Sacubitril/Valsartan: From Clinical Trials to Real-world Experience.
1/2018	Effect of sacubitril/valsartan on recurrent events in the Prospective comparison of ARNI with ACEI to Determine Impact on Global Mortality and morbidity in Heart Failure trial (PARADIGM-HF).
1/2018	Renal Effects and Associated Outcomes During Angiotensin-Neprilysin Inhibition in Heart Failure.

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Akshay S Desai Research Topics

Disease

157	Heart Failure 10/2022 - 08/2006
14	Chronic Renal Insufficiency 10/2020 - 12/2009
14	Hyperkalemia 10/2019 - 11/2007
13	Type 2 Diabetes Mellitus (MODY) 01/2022 - 10/2011
13	Cardiomyopathies (Cardiomyopathy) 01/2022 - 12/2004
9	Diabetes Mellitus 01/2022 - 11/2015
9	Heart Arrest (Cardiac Arrest) 01/2022 - 12/2012
9	Cardiovascular Diseases (Cardiovascular Disease) 01/2021 - 12/2012
7	Anemia 04/2022 - 10/2011
7	Myocardial Infarction 01/2022 - 12/2004
6	Sudden Death 01/2022 - 12/2004
6	Atrial Fibrillation 01/2022 - 01/2018
6	Chronic Obstructive Pulmonary Disease (COPD) 12/2021 - 12/2017
6	Hypotension (Low Blood Pressure) 10/2019 - 12/2012
6	Hypokalemia 01/2019 - 09/2013
6	Stroke (Strokes) 01/2018 - 12/2012
5	Heart Diseases (Heart Disease) 01/2022 - 12/2014
4	Systolic Heart Failure 04/2022 - 03/2013
4	Coronary Artery Disease (Coronary Atherosclerosis) 01/2018 - 12/2012
4	Chronic Kidney Failure (Chronic Renal Failure) 04/2016 - 11/2011
3	Cardiac Sudden Death (Sudden Cardiac Arrest) 10/2020 - 12/2004
3	Respiratory Sounds (Crackle) 01/2019 - 09/2013
3	Albuminuria 11/2018 - 09/2011
3	Fibrosis (Cirrhosis) 05/2017 - 01/2010
2	Human Influenza (Influenza) 01/2021 - 02/2016
2	Death (Near-Death Experience) 12/2019 - 01/2018
2	Angioedema 10/2019 - 09/2014
2	Atherosclerosis 05/2019 - 01/2019
2	Edema (Dropsy) 01/2019 - 01/2019
2	Frailty 11/2018 - 01/2018
2	Insulin Resistance 01/2017 - 01/2011
2	Left Ventricular Dysfunction 07/2014 - 09/2013
1	Cardiac Arrhythmias (Arrythmia) 01/2022
1	Shock 01/2022
1	Hypercholesterolemia 01/2022
1	Neoplasms (Cancer) 01/2021
1	Pneumonia (Pneumonitis) 01/2021

Drug/Important Bio-Agent (IBA)

41	sacubitril and valsartan sodium hydrate drug combinationIBA 01/2022 - 07/2014
37	Mineralocorticoid Receptor AntagonistsIBA 01/2022 - 12/2009
28	Neprilysin (Neutral Endopeptidase)IBA 12/2021 - 09/2013
26	Enalapril FDA LinkGeneric 01/2022 - 07/2014
22	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2022 - 09/2011
22	Spironolactone (Aldactone)FDA LinkGeneric 01/2022 - 11/2007
22	Angiotensin Receptors (Angiotensin II Receptor)IBA 12/2021 - 09/2013
22	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2021 - 11/2007
15	Natriuretic PeptidesIBA 01/2022 - 01/2013
15	CreatinineIBA 12/2021 - 11/2007
14	pro-brain natriuretic peptide (1-76)IBA 01/2022 - 09/2011
12	Biomarkers (Surrogate Marker)IBA 01/2022 - 10/2011
11	dapagliflozinIBA 01/2022 - 01/2019
11	PotassiumIBA 01/2021 - 11/2007
10	DiureticsIBA 01/2022 - 06/2008
10	Angiotensin Receptor AntagonistsIBA 12/2021 - 12/2009
10	aliskiren FDA Link 10/2020 - 02/2012
9	paragonIBA 01/2022 - 01/2017
8	Darbepoetin alfa (Aranesp)FDA Link 04/2022 - 10/2011
8	candesartanIBA 08/2021 - 11/2007
7	Irbesartan FDA LinkGeneric 08/2021 - 03/2010
6	SodiumIBA 12/2021 - 12/2017
6	AngiotensinsIBA 01/2021 - 09/2014
5	Glucose (Dextrose)FDA LinkGeneric 11/2021 - 01/2011
5	Pharmaceutical PreparationsIBA 01/2019 - 11/2007
5	Hemoglobins (Hemoglobin)IBA 05/2018 - 03/2013
4	Troponin T (Troponin T1)IBA 01/2022 - 10/2011
4	Valsartan (Vals)FDA Link 12/2021 - 01/2017
4	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 04/2016 - 09/2013
3	Insulin (Novolin)FDA Link 01/2019 - 01/2011
3	AlbuminsIBA 11/2018 - 09/2011
2	Peptides (Polypeptides)IBA 01/2021 - 01/2020
2	ReninIBA 01/2021 - 02/2012
2	Influenza Vaccines (Influenza Vaccine)FDA Link 01/2021 - 02/2016
2	Uric Acid (Urate)IBA 11/2020 - 01/2018
2	Sodium-Glucose Transporter 2 InhibitorsIBA 01/2020 - 11/2019
2	Sodium Potassium Chloride Symporter Inhibitors (Loop Diuretics)IBA 01/2020 - 01/2019
2	Sodium-Glucose Transport ProteinsIBA 11/2019 - 01/2019
2	Thyroid HormonesIBA 05/2019 - 01/2019
2	Trinitrotoluene (TNT)IBA 01/2019 - 11/2011
2	TroponinIBA 11/2018 - 01/2018
2	Renin InhibitorsIBA 04/2016 - 12/2012
1	IronIBA 04/2022
1	CytokinesIBA 04/2022
1	Ferritins (Ferritin)IBA 04/2022
1	Growth Differentiation Factor 15IBA 04/2022
1	oxidized low density lipoproteinIBA 01/2022
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2022
1	empagliflozinIBA 11/2021
1	Galectin 3 (LGALS3)IBA 01/2021

Therapy/Procedure

59	Therapeutics 10/2022 - 12/2004
7	Implantable Defibrillators (Implantable Cardioverter-Defibrillator) 01/2022 - 12/2004
4	Defibrillators (Defibrillator) 01/2022 - 12/2004
4	Palliative Care (Palliative Therapy) 01/2021 - 01/2018
4	Patient Readmission 01/2020 - 08/2003
3	Transplantation 09/2015 - 11/2012
2	Cardiac Resynchronization Therapy 01/2022 - 01/2020
2	Drug Tapering 01/2019 - 11/2007
2	Heart Transplantation (Grafting, Heart) 01/2015 - 01/2010
2	Heart-Assist Devices 01/2014 - 01/2010
2	Renal Replacement Therapy (Therapies, Renal Replacement) 12/2012 - 11/2011
1	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 12/2021
1	Polypharmacy 11/2021